Holes in SOCS in primary mediastinal large B-cell lymphoma

被引：2

作者：

Campo, E ^{[1
]}

机构：

[1] Univ Barcelona, E-08007 Barcelona, Spain

来源：

BLOOD | 2005年 / 105卷 / 06期

关键词：

D O I：

10.1182/blood-2004-12-4957

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Primary mediastinal large B-cell lymphomas have frequent inactivating mutations of SOCS1 that impair JAK2 degradation and in turn maintain a constitutive activation of the JAK2/STAT pathway in these lymphomas.

引用

页码：2244 / 2245

页数：2

共 7 条

[1]

Bentz M, 2001, GENE CHROMOSOME CANC, V30, P393, DOI 10.1002/1098-2264(2001)9999:9999<::AID-GCC1105>3.0.CO

[2]

2-I

[3] Tissue inhibitor of metalloproteinase 1 (TIMP-1) promotes plasmablastic differentiation of a Burkitt lymphoma cell line: implications in the pathogenesis of plasmacytic/plasmablastic tumors [J].

Guedez, L ;

Martinez, A ;

Zhao, SM ;

Vivero, A ;

Pittaluga, S ;

Stetler-Stevenson, M ;

Raffeld, M ;

Stetler-Stevenson, WG .

BLOOD, 2005, 105 (04) :1660-1668

[4] Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma [J].

Guiter, C ;

Dusanter-Fourt, I ;

Copie-Bergman, C ;

Boulland, ML ;

le Gouvello, S ;

Gaulard, P ;

Leroy, K ;

Castellano, F .

BLOOD, 2004, 104 (02) :543-549

[5] Cyclin D1 expression in mantle cell lymphoma is accompanied by downregulation of cyclin D3 and is not related to the proliferative activity [J].

Ott, MM ;

Bartkova, J ;

Bartek, J ;

Durr, A ;

Fischer, L ;

Ott, G ;

MullerHermelink, HK ;

Kreipe, H .

BLOOD, 1997, 90 (08) :3154-3159

[6] Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma [J].

Rosenwald, A ;

Wright, G ;

Leroy, K ;

Yu, X ;

Gaulard, P ;

Gascoyne, RD ;

Chan, WC ;

Zhao, T ;

Haioun, C ;

Greiner, TC ;

Weisenburger, DD ;

Lynch, JC ;

Vose, J ;

Armitage, JO ;

Smeland, EB ;

Kvaloy, S ;

Holte, H ;

Delabie, J ;

Campo, E ;

Montserrat, E ;

Lopez-Guillermo, A ;

Ott, G ;

Muller-Hermelink, HK ;

Connors, JM ;

Braziel, R ;

Grogan, TM ;

Fisher, RI ;

Miller, TP ;

LeBlanc, M ;

Chiorazzi, M ;

Zhao, H ;

Yang, LM ;

Powell, J ;

Wilson, WH ;

Jaffe, ES ;

Simon, R ;

Klausner, RD ;

Staudt, LM .

JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 198 (06) :851-862

[7] The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma [J].

Savage, KJ ;

Monti, S ;

Kutok, JL ;

Cattoretti, G ;

Neuberg, D ;

de Leval, L ;

Kurtin, P ;

Dal Cin, P ;

Ladd, C ;

Feuerhake, F ;

Aguiar, RCT ;

Li, SG ;

Salles, G ;

Berger, F ;

Jing, W ;

Pinkus, GS ;

Habermann, T ;

Dalla-Favera, R ;

Harris, NL ;

Aster, JC ;

Golub, TR ;

Shipp, MA .

BLOOD, 2003, 102 (12) :3871-3879

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