Adenosine receptors as targets for drug development

被引：74

作者：

Fredholm, BB ^{[1
]}

机构：

[1] Karolinska Inst, Dept Physiol & Pharmacol, S-17177 Stockholm, Sweden

来源：

DRUG NEWS & PERSPECTIVES | 2003年 / 16卷 / 05期

关键词：

D O I：

10.1358/dnp.2003.16.5.829316

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Adenosine is a ubiquitous autacoid that acts on four defined receptors, named A(1), A(2A), A(2B) and A(3). Although the biological activity of adenosine has been known for more than 70 years and the existence of specific receptors for more than 25 years, it is only now that the full potential for drug development is becoming clear. Among some of the conditions for which adenosine receptor-based therapy might be used are Parkinson's disease, hypoxia/ischemia, epilepsy, kidney disease and asthma. (C) 2003 Prous Science. All rights reserved.

引用

页码：283 / 289

页数：7

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