Biggest virus molecular structure yet!

被引：9

作者：

Johnson, JE ^{[1
]}

Reddy, VS ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA

来源：

NATURE STRUCTURAL BIOLOGY | 1998年 / 5卷 / 10期

关键词：

D O I：

10.1038/2288

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The blue tongue virus core (BTVC) particle is the biggest molecular structure determined to date by X-ray crystallography. The atomic model shows that the inner core particle of 120 VP3 subunits guides the assembly of an outer shell with 780 VP7subunits. The structure may lead to new targets for particle based anti-viral agents and to experiments to refine the details of the proposed virus assembly pathway.

引用

页码：849 / 854

页数：6

共 23 条

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