Genome streamlining in a cosmopolitan oceanic bacterium

被引：831

作者：

Giovannoni, SJ ^{[1
]}

Tripp, HJ

Givan, S

Podar, M

Vergin, KL

Baptista, D

Bibbs, L

Eads, J

Richardson, TH

Noordewier, M

Rappé, MS

Short, JM

Carrington, JC

Mathur, EJ

机构：

[1] Oregon State Univ, Dept Microbiol, Corvallis, OR 97331 USA

[2] Oregon State Univ, Ctr Gene Res & Biotechnol, Corvallis, OR 97331 USA

[3] Diversa Corp, San Diego, CA 92121 USA

[4] Univ Hawaii, Sch Ocean & Earth Sci & Technol, Hawaii Inst Marine Biol, Kaneohe, HI 96744 USA

来源：

SCIENCE | 2005年 / 309卷 / 5738期

关键词：

D O I：

10.1126/science.1114057

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The SAR11 clade consists of very small, heterotrophic marine alpha-proteobacteria that are found throughout the oceans, where they account for about 25% of all microbial cells. Pelagibacter ubique, the first cultured member of this clade, has the smallest genome and encodes the smallest number of predicted open reading frames known for a free-living microorganism. In contrast to parasitic bacteria and archaea with small genomes, P. ubique has complete biosynthetic pathways for all 20 amino acids and all but a few cofactors. P. ubique has no pseudogenes, introns, transposons, extrachromosomat elements, or inteins; few paralogs; and the shortest intergenic spacers yet observed for any cell.

引用

页码：1242 / 1245

页数：4

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