Three-dimensional optical-tomographic localization of changes in absorption coefficients in the human brain

被引：5

作者：

Bluestone, A ^{[1
]}

Abdoulaev, G ^{[1
]}

Barbour, R ^{[1
]}

Schmitz, C ^{[1
]}

Hielscher, AH ^{[1
]}

机构：

[1] Suny Downstate Med Ctr, Dept Pathol, Brooklyn, NY 11203 USA

来源：

OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE IV | 2001年 / 4250卷

关键词：

diffuse optical tomography; brain imaging; three-dimensional imaging; inverse-problem;

D O I：

10.1117/12.434496

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We report on the first three dimensional tomographic localization of vascular reactivity in the brain. Using a model-based iterative image reconstruction algorithm we show the spatial distribution of changes in the absorption coefficient caused by changes in blood volume. Unlike currently available topographic reconstruction techniques, three-dimensional, volumetric reconstruction schemes promise to be capable of spatially distinguishing between signals originating in the cerebral cortex from those originating in the overlying tissues.

引用

页码：258 / 268

页数：11

共 25 条

[1]

ABDOULAEV G, 2000, P 3 EUR C NUM MATH A, P407

[2] A gradient-based optimisation scheme for optical tomography [J].

Arridge, SR ;

Schweiger, M .

OPTICS EXPRESS, 1998, 2 (06) :213-226

[3] Noninvasive functional imaging of human brain using light [J].

Benaron, DA ;

Hintz, SR ;

Villringer, A ;

Boas, D ;

Kleinschmidt, A ;

Frahm, J ;

Hirth, C ;

Obrig, H ;

van Houten, JC ;

Kermit, EL ;

Cheong, WF ;

Stevenson, DK .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2000, 20 (03) :469-477

[4]

BRAMBLE JH, 1990, MATH COMPUT, V55, P1, DOI 10.1090/S0025-5718-1990-1023042-6

[5] Giving reverse differentiation a helping hand [J].

Christianson, DB ;

Davies, AJ ;

Dixon, LCW ;

Roy, R ;

VanderZee, P .

OPTIMIZATION METHODS & SOFTWARE, 1997, 8 (01) :53-67

[6]

CHURCH EF, 1948, ELEMENTS PHOTOGRAMME

[7] Reverse differentiation sind the inverse diffusion problem [J].

Davies, AJ ;

Christianson, DB ;

Dixon, LCW ;

Roy, R ;

vanderZee, P .

ADVANCES IN ENGINEERING SOFTWARE, 1997, 28 (04) :217-221

[8] Non-invasive optical monitoring of the newborn piglet brain using continuous-wave and frequency-domain spectroscopy [J].

Fantini, S ;

Hueber, D ;

Franceschini, MA ;

Gratton, E ;

Rosenfeld, W ;

Stubblefield, PG ;

Maulik, D ;

Stankovic, MR .

PHYSICS IN MEDICINE AND BIOLOGY, 1999, 44 (06) :1543-1563

[9] On-line optical imaging of the human brain with 160-ms temporal resolution [J].

Franceschini, MA ;

Toronov, V ;

Filiaci, ME ;

Gratton, E ;

Fantini, S .

OPTICS EXPRESS, 2000, 6 (03) :49-57

[10] Dynamic brain imaging: Event-related optical signal (EROS) measures of the time course and localization of cognitive-related activity [J].

Gratton, G ;

Fabiani, M .

PSYCHONOMIC BULLETIN & REVIEW, 1998, 5 (04) :535-563

← 1 2 3 →