Cognitive reserve and lifestyle

被引:551
作者
Scarmeas, N
Stern, Y
机构
[1] Columbia Univ, Coll Phys & Surg, New York, NY USA
[2] Columbia Univ, Taub Inst Res Alzheimers Dis & Aging Brain, Dept Neurol, Cognit Neurosci Div, New York, NY USA
关键词
D O I
10.1076/jcen.25.5.625.14576
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
The concept of cognitive reserve (CR) suggests that innate intelligence or aspects of life experience like educational or occupational attainments may supply reserve, in the form of a set of skills or repertoires that allows some people to cope with progressing Alzheimer's disease (AD) pathology better than others. There is epidemiological evidence that lifestyle characterized by engagement in leisure activities of intellectual and social nature is associated with slower cognitive decline in healthy elderly and may reduce the risk of incident dementia. There is also evidence from functional imaging studies that subjects engaging in such leisure activities can clinically tolerate more AD pathology. It is possible that aspects of life experience like engagement in leisure activities may result in functionally more efficient cognitive networks and therefore provide a CR that delays the onset of clinical manifestations of dementia.
引用
收藏
页码:625 / 633
页数:9
相关论文
共 52 条
[1]  
Alexander GE, 1997, AM J PSYCHIAT, V154, P165
[2]   Cognitive Functioning of Older People in Relation to Social and Personality Variables [J].
Arbuckle, Tannis Y. ;
Gold, Dolores ;
Andres, David .
PSYCHOLOGY AND AGING, 1986, 1 (01) :55-62
[3]   THE ROLE OF PSYCHOSOCIAL CONTEXT, AGE, AND INTELLIGENCE IN MEMORY PERFORMANCE OF OLDER MEN [J].
ARBUCKLE, TY ;
GOLD, DP ;
ANDRES, D ;
SCHWARTZMAN, A ;
CHAIKELSON, J .
PSYCHOLOGY AND AGING, 1992, 7 (01) :25-36
[4]  
Balfour JL, 2001, NEUROLOGY, V56, pA239
[5]   INCIDENCE AND RELATIVE RISK OF DEMENTIA IN AN URBAN ELDERLY POPULATION - FINDINGS OF A PROSPECTIVE FIELD-STUDY [J].
BICKEL, H ;
COOPER, B .
PSYCHOLOGICAL MEDICINE, 1994, 24 (01) :179-192
[6]   Health habits and risk of cognitive impairment and dementia in old age: A prospective study on the effects of exercise, smoking and alcohol consumption [J].
Broe, GA ;
Creasey, H ;
Jorm, AF ;
Bennett, HP ;
Casey, B ;
Waite, LM ;
Grayson, DA ;
Cullen, J .
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, 1998, 22 (05) :621-623
[7]   Activity levels and cognitive functioning in an elderly community sample [J].
Christensen, H ;
Korten, A ;
Jorm, AF ;
Henderson, AS ;
Scott, R ;
Mackinnon, AJ .
AGE AND AGEING, 1996, 25 (01) :72-80
[8]   PATTERNS OF MEMORY LOSS IN 3 ELDERLY SAMPLES [J].
CRAIK, FIM ;
BYRD, M ;
SWANSON, JM .
PSYCHOLOGY AND AGING, 1987, 2 (01) :79-86
[9]   AEROBIC EXERCISE TRAINING AND IMPROVED NEUROPSYCHOLOGICAL FUNCTION OF OLDER INDIVIDUALS [J].
DUSTMAN, RE ;
RUHLING, RO ;
RUSSELL, EM ;
SHEARER, DE ;
BONEKAT, HW ;
SHIGEOKA, JW ;
WOOD, JS ;
BRADFORD, DC .
NEUROBIOLOGY OF AGING, 1984, 5 (01) :35-42
[10]   Memory performance in relation to age, verbal ability, and activity [J].
Erber, JT ;
Szuchman, LT .
EXPERIMENTAL AGING RESEARCH, 1996, 22 (01) :59-72