Thioctic acid amides: convenient tethers for achieving low nonspecific protein binding to carbohydrates presented on gold surfaces

被引:44
作者
Karamanska, R [1 ]
Mukhopadhyay, B [1 ]
Russell, DA [1 ]
Field, RA [1 ]
机构
[1] Univ E Anglia, Sch Chem Sci & Pharm, Ctr Carbohydrate Chem, Norwich NR4 7TJ, Norfolk, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1039/b503843j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The thioctic acid amides of 2'-aminoethyl alpha-D-mannopyranoside and 2'-aminoethyl alpha-1,3-D-mannopyranosyl (alpha-1,6-D-mannopyranosyl)-alpha- D-mannopyranoside presented on both planar and nanoparticle gold surfaces give higher specific and lower non-specific protein binding than the related 2'-thioethyl glycosides.
引用
收藏
页码:3334 / 3336
页数:3
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