Elevated interleukin-8 concentrations in cervical secretions are associated with preterm labour

被引：18

作者：

Dowd, J

Laham, N

Rice, G

Brennecke, S

Permezel, M

机构：

[1] Univ Melbourne, Royal Hosp Women, Perinatal Res Ctr, Melbourne, Vic 3053, Australia

[2] Univ Melbourne, Royal Hosp Women, Dept Obstet & Gynaecol, Melbourne, Vic 3053, Australia

来源：

GYNECOLOGIC AND OBSTETRIC INVESTIGATION | 2001年 / 51卷 / 03期

关键词：

interleukin-8; preterm labour; cervical secretions;

D O I：

10.1159/000052917

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The aim of this study was to assess the potential clinical utility of interleukin-8 (IL-8) present in cervical secretions as a marker of preterm labour and delivery, Samples of cervical mucus from 91 pregnant women were assessed for the presence and concentration of IL-8, Two samples were collected (at 18 +/- 2 and 28 +/- 2.5 weeks of gestation) and correlated with cervicovaginal microbiology and cervical length, as measured by transvaginal ultrasound, The IL-8 concentration at 28/40 was significantly higher in women who went on to deliver preterm (p < 0.01), and there was a greater than five-fold increase from 18 to 28 weeks in 6/7 of these women. Copyright (C) 2001 S. Karger AG, Basel.

引用

收藏

页码：165 / 168

页数：4

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