Physiologically-based kinetic modelling (PBK modelling): Meeting the 3Rs agenda

被引：50

作者：

d'Yvoire, Michel Bouvier ^{[1
]}

Prieto, Pilar ^{[1
]}

Blaauboer, Bas J. ^{[1
,2
]}

Bois, Frederic Y. ^{[3
]}

Boobis, Alan ^{[4
]}

Brochot, Celine ^{[3
]}

Coecke, Sandra ^{[1
]}

Freidig, Andreas ^{[5
]}

Gundert-Remy, Ursula ^{[6
]}

Hartung, Thomas ^{[1
]}

Jacobs, Miriam N. ^{[1
]}

Lave, Thierry ^{[7
]}

Leahy, David E. ^{[8
]}

Lennernaes, Hans ^{[9
]}

Loizou, George D. ^{[10
]}

Meek, Bette ^{[11
]}

Pease, Camilla ^{[12
]}

Rowland, Malcolm ^{[13
]}

Spendiff, Martin ^{[10
]}

Yang, Jiansong ^{[14
]}

Zeilmaker, Marco ^{[15
]}

机构：

[1] Commiss European Communities, Joint Res Ctr, IHCP, ECVAM, I-21020 Ispra, Italy

[2] Univ Utrecht, Inst Risk Assessment Sci, Utrecht, Netherlands

[3] Inst Natl Environm Ind & Risques, Verneuil En Halatte, France

[4] Univ London Imperial Coll Sci Technol & Med, London, England

[5] TNO Nutrit & Food Res, Dept Physiol Sci, Zeist, Netherlands

[6] Bundesinst Riskobewertung, Berlin, Germany

[7] F Hoffmann La Roche & Co Ltd, Roche Pharma Res, CH-4002 Basel, Switzerland

[8] Univ Newcastle Upon Tyne, Mol Infromat Grp, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[9] Uppsala Univ, Dept Pharm, Biomed Ctr, Uppsala, Sweden

[10] Computat Toxicol Hlth Sci Hlth & Safety Lab, Buxton, England

[11] Hlth Canada, Existing Substances Div, Ottawa, ON, Canada

[12] Unilever Res Labs Colworth, Safety & Environm Assurance Ctr, Sharnbrook MK44 1LQ, Beds, England

[13] Univ Manchester, Sch Pharm & Pharmaceut Sci, Manchester, Lancs, England

[14] SimCYP Ltd, Sheffield, S Yorkshire, England

[15] Natl Inst Publ Hlth & Environm, Ctr Subst & Integrated Risk Assessment, NL-3720 BA Bilthoven, Netherlands

来源：

ATLA-ALTERNATIVES TO LABORATORY ANIMALS | 2007年 / 35卷 / 06期

关键词：

D O I：

10.1177/026119290703500606

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

[No abstract available]

引用

页码：661 / 671

页数：11

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