Placental umbilical cord blood transfusion in acute ischaemic stroke

被引:12
作者
Chaudhuri, Abhijit
Hollands, Peter
Bhattacharya, Niranjan
机构
[1] Queens Hosp, Essex Ctr Neurol Sci, Romford RM7 0AG, Essex, England
[2] UK Cord Blood Bank, London, England
[3] Vidyasagar State Hosp, Kolkata, India
[4] BP Poddar Hosp, Kolkata, India
关键词
D O I
10.1016/j.mehy.2007.01.091
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 [基础医学];
摘要
Stroke is a major cause of neurological disability across all countries in the world. Functional recovery after stroke is limited because of neuronal death and degeneration. Although early reperfusion therapy may improve outcome, thrombolysis does not reverse ischaemic neuronal death and carries the risk of cerebral haemorrhage. Early trials of stem cell therapy in promoting functional recovery after completed stroke remain inconclusive. Based on experimental data, we propose human umbilical cord blood transfusion as a possible therapy for ischaemic cerebral stroke to aid functional recovery. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1267 / 1271
页数:5
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