A human intracranial study of long-range oscillatory coherence across a frontal-occipital-hippocampal brain network during visual object processing

被引：154

作者：

Sehatpour, Pejman ^{[1
,2
]}

Molholm, Sophie ^{[1
,2
]}

Schwartz, Theodore H. ^{[3
]}

Mahoney, Jeannette R. ^{[1
]}

Mehta, Ashesh D. ^{[4
]}

Javitt, Daniel C. ^{[1
,2
]}

Stanton, Patric K. ^{[5
,6
]}

Foxe, John J. ^{[1
,2
]}

机构：

[1] Nathan S Kline Inst Psychiat Res, Program Cognit Neurosci & Schizophrenia, Cognit Neurophysiol Lab, Orangeburg, NY 10962 USA

[2] CUNY City Coll, Dept Psychol, Program Cognit Neurosci, New York, NY 10031 USA

[3] Weill Cornell Med Coll, Dept Neurol Surg, New York, NY 10021 USA

[4] Long Isl Jewish Med Ctr, Comprehens Epilepsy Ctr, New Hyde Pk, NY 11040 USA

[5] New York Med Coll, Dept Cell Biol & Anat, Valhalla, NY 10595 USA

[6] New York Med Coll, Dept Neurol, Valhalla, NY 10595 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2008年 / 105卷 / 11期

关键词：

vision; EEG; beta oscillations; hippocampus; perceptual closure;

D O I：

10.1073/pnas.0708418105

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Visual object-recognition is thought to involve activation of a distributed network of cortical regions, nodes of which include the lateral prefrontal cortex, the so-called lateral occipital complex (LOC), and the hippocampal formation. It has been proposed that long-range oscillatory synchronization is a major mode of coordinating such a distributed network. Here, intracranial recordings were made from three humans as they performed a challenging visual object-recognition task that required them to identify barely recognizable fragmented line-drawings of common objects. Subdural electrodes were placed over the prefrontal cortex and LOC, and depth electrodes were placed within the hippocampal formation. Robust beta-band coherence was evident in all subjects during processing of recognizable fragmented images. Significantly lower coherence was evident during processing of unrecognizable scrambled versions of the same. The results indicate that transient beta-band oscillatory coupling between these three distributed cortical regions may reflect a mechanism for effective communication during visual object processing.

引用

页码：4399 / 4404

页数：6

共 65 条

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