Focale: Study of systolic and diastolic heart failure in a French elderly population

被引:6
作者
Dubourg, Olivier [1 ]
Gueret, Pascal
Beauchet, Alain [1 ]
Nisse-Durgeat, Sophie [2 ]
Ducardonnet, Alain [3 ]
机构
[1] Univ Versailles St Quentin Yvelines, Hop Ambroise Pare, AP HP Boulogne Billancourt, Versailles, France
[2] Labs Takeda, Puteaux La Defense, France
[3] Clin Sport St Francois, Paris, France
关键词
cross-sectional study; heart failure; prevalence; diastolic heart failure;
D O I
10.1016/j.ijcard.2007.01.050
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Context: The epidemic of heart failure (HF) in France has not been fully investigated and data on both the systolic and diastolic forms are limited. Objectives: To determine the prevalence, aetiology and treatments of both forms in French patients over 65 with HF (NYHA grade II-IV). Participants: Cross-sectional study of 446 patients with HF recruited by 273 randomly selected cardiologists in France, with echocardiography and ECG available for central reading. Main measurements: Prevalence of diastolic (DHF) and systolic (SHF) HF using the left ventricular ejection fraction (LVEF). Results: DHF, with a mean LVEF of 57.6 +/- 8.0%, was reported for 245 (54.9%) patients and SHF, with a mean LVEF of 33.33 +/- 8.0% was reported for 201 (45.1%) patients. Men were more prone to suffer SHF than DHF whereas for women the reverse was true. As compared to SHF, DHF endsystolic and enddiastolic volumes were smaller, the thickness/radius ratio was greater, with a longer E-wave deceleration time and a shorter peak filling rate. Aetiology and treatments were similar in both types of HF, except for ACE inhibitors and aldosterone antagonists, which were more frequently prescribed in SHF. Conclusion: This observational study provides further knowledge of SHF and DHF in outpatients. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:188 / 192
页数:5
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