Eucalyptone G, a new phloroglucinol derivative and other constituents from Eucalyptus globulus Labill

被引:46
作者
Mohamed, Gamal A. [1 ]
Ibrahim, Sabrin R. M. [2 ]
机构
[1] Al Azhar Univ, Fac Pharm, Dept Pharmacognosy, Assiut 71524, Egypt
[2] Assiut Univ, Fac Pharm, Dept Pharmacognosy, Assiut 71526, Egypt
关键词
Eucalyptus globulus Labill; Myrtaceae; eucalyptone G; antibacterial activity;
D O I
10.3998/ark.5550190.0008.f27
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new pholoroglucinol derivative named eucalyptone G (4) together with nine known compounds (1-3, 5-10) were isolated for the first time from the ethyl acetate fraction of the bark of small twigs of Eucalyptus globulus Labill. Their chemical structures were established on the basis of physical, chemical and spectroscopic methods 1D (H-1 and C-13) NMR and 2D (COSY, HMQC and HMBC) NMR in addition to mass spectrometry and comparison with literature data. Eucalyptone G displayed antibacterial activity against Bacillus subtilis, Staphylococcus aureus and Escherichia coli.
引用
收藏
页码:281 / 291
页数:11
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