Mild synthesis of polyfunctional benzimidazoles and indoles by the reduction of functionalized nitroarenes with phenylmagnesium chloride

被引：46

作者：

Dohle, W ^{[1
]}

Staubitz, A ^{[1
]}

Knochel, P ^{[1
]}

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2003年 / 9卷 / 21期

关键词：

Grignard reaction; heterocycles; magnesium nitrenoids; nitrenes;

D O I：

10.1002/chem.200305090

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Phenylmagnesium chloride has been used for the conversion of selected nitroarenes into nitrenes. Their insertion into a neighboring sp(2) C-H bond yielded functionalized heterocycles. A novel and mild synthesis of polyfunctional benzimidazoles and indoles is described.

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收藏

页码：5323 / 5331

页数：9

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