One- and two-dimensional NMR study of complexation of ursodeoxycholic acid with beta-cyclodextrin

被引：21

作者：

Mucci, A

Schenetti, L

Vandelli, MA

Forni, F

Ventura, P

Salvioli, G

机构：

[1] UNIV MODENA,DIPARTIMENTO SCI FARMACEUT,I-41100 MODENA,ITALY

[2] UNIV MODENA,CATTEDRA GERIAT & GERONTOL,I-41100 MODENA,ITALY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2 | 1996年 / 11期

关键词：

D O I：

10.1039/p29960002347

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The interaction of ursodeoxycholic acid (UDCA) with beta-cyclodextrin (beta-CD) is investigated through one and two-dimensional (ROESY) NMR spectroscopy. The relative orientation of host and guest is unequivocally established: the aliphatic side chain of UDCA enters the torus of B-CD on the side of the secondary hydroxy groups.

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收藏

页码：2347 / 2349

页数：3

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