Overexpression of p53 in different subtypes of intestinal metaplasia and gastric cancer

被引：20

作者：

Wu, WS

Shun, CT

Lee, WC

Chen, CJ

Wang, HP

Lee, WJ

Sheu, JC

Lin, JT

机构：

[1] Natl Taiwan Univ Hosp, Dept Internal Med, Taipei, Taiwan

[2] Natl Taiwan Univ Hosp, Dept Pathol, Taipei, Taiwan

[3] Natl Taiwan Univ, Coll Publ Hlth, Grad Inst Epidemiol, Taipei, Taiwan

[4] Natl Taiwan Univ Hosp, Dept Emergency Med, Taipei, Taiwan

[5] Natl Taiwan Univ Hosp, Dept Surg, Taipei, Taiwan

来源：

BRITISH JOURNAL OF CANCER | 1998年 / 78卷 / 07期

关键词：

gastric cancer; intestinal metaplasia; p53; overexpression;

D O I：

10.1038/bjc.1998.611

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

p53 immunostaining was evaluated in cancerous epithelia and adjacent intestinal metaplasia of 135 gastric cancer specimens. The differential p53 overexpression in different subtypes of intestinal metaplasia and gastric cancer suggests that type III intestinal metaplasia is the commonest lesion in dysplasia-carcinoma transition, particularly in the intestinal type of gastric cancer.

引用

页码：971 / 973

页数：3

共 24 条

[1] PRECURSORS OF GASTRIC-CARCINOMA - A CRITICAL-REVIEW WITH A BRIEF DESCRIPTION OF EARLY (CURABLE) GASTRIC-CANCER [J].