Apoptosis - Molecular mechanisms and biomedical implications

被引:101
作者
McConkey, DJ
Zhivotovsky, B
Orrenius, S
机构
[1] KAROLINSKA INST, DIV TOXICOL, INST ENVIRONM MED, S-17177 STOCKHOLM, SWEDEN
[2] MD ANDERSON CANC CTR, DEPT CELL BIOL, HOUSTON, TX 77030 USA
关键词
D O I
10.1016/0098-2997(95)00006-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Apoptosis is a distinct form of cell death of importance in tissue development and homeostasis and in several diseases. This review summarizes current knowledge about the regulation and molecular mechanisms of apoptosis and discusses the potential role of disregulated apoptosis in several major diseases. Finally, we speculate that modulation of apoptosis may be a target in future drug therapy. Copyright (C) 1996 Elsevier Science Ltd.
引用
收藏
页码:1 / +
页数:1
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