Reducing Mortality in Severe Sepsis and Septic Shock

被引：54

作者：

Levinson, Andrew T. ^{[1
]}

Casserly, Brian P. ^{[1
]}

Levy, Mitchell M. ^{[1
]}

机构：

[1] Brown Univ, Div Pulm Crit Care & Sleep Med, Warren Alpert Med Sch, Providence, RI 02912 USA

来源：

SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE | 2011年 / 32卷 / 02期

关键词：

Sepsis; septic shock; critical care; Surviving Sepsis Campaign; GOAL-DIRECTED THERAPY; INTENSIVE INSULIN THERAPY; EARLY LACTATE CLEARANCE; ACTIVATED PROTEIN-C; CORTICOSTEROID TREATMENT; FLUID RESUSCITATION; CARDIOVASCULAR DYSFUNCTION; CLINICAL-PRACTICE; GLUCOSE CONTROL; ORGAN FAILURE;

D O I：

10.1055/s-0031-1275532

中图分类号：

R4 [临床医学];

学科分类号：

100218 [急诊医学];

摘要：

Severe sepsis is one of the most common reasons for critically ill patients to be admitted to an intensive care unit (ICU) and has very high associated morbidity and mortality. The Surviving Sepsis Campaign was initiated with the hope that mortality might be reduced by standardizing care informed by data from an increasing number of clinical trials. Important methods for reducing mortality identified by recent studies include aggressive fluid resuscitation, early goal-directed therapy (EGDT), early administration of antibiotics, and the administration of activated protein C to eligible patients.

引用

页码：195 / 205

页数：11

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