PSYCHOMETRIC VALIDATION OF A PATIENT-REPORTED MEASURE OF PHYSICAL FUNCTIONING IN SPORADIC INCLUSION BODY MYOSITIS

被引：12

作者：

Williams, Valerie ^{[1
]}

Coles, Theresa ^{[1
]}

Gnanasakthy, Ari ^{[1
]}

Demuro, Carla ^{[1
]}

Yarr, Stuart ^{[1
]}

Williams, Nicole ^{[1
]}

Lowes, Linda ^{[2
]}

Alfano, Lindsay ^{[2
]}

Tseng, Brian ^{[3
]}

机构：

[1] RTI Hlth Solut, 200 Pk Off Dr, Res Triangle Pk, NC 27709 USA

[2] Nationwide Childrens Hosp, Columbus, OH USA

[3] Novartis Pharmaceut, E Hanover, NJ USA

来源：

MUSCLE & NERVE | 2016年 / 54卷 / 04期

关键词：

patient-reported outcomes; physical functioning; psychometric evaluation; sporadic inclusion body myositis; validation Additional supporting information may be found in the online version of this article; RATING-SCALE; PREVALENCE;

D O I：

10.1002/mus.25080

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Introduction: To assess self-reported physical functioning in patients with sporadic inclusion body myositis (sIBM), the sIBM Physical Functioning Assessment (sIFA) was developed. This research establishes the validity, reliability, and responsiveness of the sIFA in patients with sIBM. Methods: Data from 3 small, noninterventional, observational studies were analyzed. Several measures of physical function were included to assess validity. Reliability (Cronbach alpha, test-retest intraclass correlations), construct validity (correlations, analyses of variance), and responsiveness (effect size estimates) were evaluated. Results: Cronbach alphas (range = 0.86-0.91) and test-retest reliability (0.91) were highly satisfactory. Correlations with other measures provided evidence of convergent validity. sIBM patients able to walk without assistive devices scored significantly better on the sIFA (means = 36.0-47.05) than those who required power mobility or wheelchairs (means = 54.9-71.5), demonstrating the discriminating ability of the sIFA. Effect size estimates of responsiveness suggested mild functional progression. Conclusions: Psychometric analyses of the sIFA demonstrate satisfactory reliability, validity, and responsiveness.

引用

页码：658 / 665

页数：8

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