Temperature management in acute neurologic disorders

被引:87
作者
Axelrod, Yekaterina K. [1 ,2 ,3 ]
Diringer, Michael N. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA
[2] Barnes Jewish Hosp, Neurol Neurosurg Intens Care Unit, St Louis, MO 63110 USA
[3] Washington Univ, Sch Med, Sect Neurol Intens Care, St Louis, MO 63110 USA
[4] Washington Univ, Sch Med, Dept Neurol Surg, St Louis, MO 63110 USA
[5] Washington Univ, Sch Med, Dept Anesthesiol, St Louis, MO 63110 USA
关键词
D O I
10.1016/j.ncl.2008.02.005
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Temperature management in acute neurologic disorders has received considerable attention in the last 2 decades. Numerous trials of hypothermia have been performed in patients with head injury, stroke, and cardiac arrest. This article reviews the physiology of thermoregulation and mechanisms responsible for hyperpyrexia. Detrimental effects of fever and benefits of normalizing elevated temperature in experimental models are discussed. This article presents a detailed analysis of trials of induced hypothermia in patients with acute neurologic insults and describes methods of fever control.
引用
收藏
页码:585 / +
页数:20
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