Novel approach for the synthesis of Fe3O4@TiO2 core-shell microspheres and their application to the highly specific capture of phosphopeptides for MALDI-TOF MS analysis

被引:120
作者
Li, Yan [1 ]
Wu, Jinsong [2 ]
Qi, Dawei [1 ]
Xu, Xiuqing [1 ]
Deng, Chunhui [1 ]
Yang, Pengyuan [1 ]
Zhang, Xiangmin [1 ]
机构
[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
[2] Fudan Univ, Shanghai Med Coll, Huashan Hosp, Dept Neurosurg,Shanghai Neurosurg Ctr, Shanghai 200400, Peoples R China
关键词
D O I
10.1039/b716055k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel approach is proposed to synthesize Fe3O4@TiO2 microspheres with a well-defined core-shell structure, and the synthesized Fe3O4@TiO2 core-shell microspheres were successfully applied for the simple and fast enrichment of phospho-peptides via direct MALDI-TOF mass spectrometry analysis.
引用
收藏
页码:564 / 566
页数:3
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