Shifting Paradigm on Bacillus thuringiensis Toxin and a Natural Model for Enterococcus faecalis Septicemia

被引:9
作者
Graf, Joerg [1 ]
机构
[1] Univ Connecticut, Dept Mol & Cell Biol, Storrs, CT 06269 USA
来源
MBIO | 2011年 / 2卷 / 04期
基金
美国国家科学基金会;
关键词
D O I
10.1128/mBio.00161-11
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The Bt toxin is widely used in agriculture both as a spray and in transgenic plants, yet its precise mode of action against lepidopterans is poorly understood. The study by Mason et al. [mBio 2(3): e00065-11, 2011] revealed that Bt toxin enables an inhabitant of the midgut, Enterococcus faecalis, to enter the hemolymph of larvae and cause septicemia, leading to death.
引用
收藏
页数:2
相关论文
共 5 条
[1]   Midgut bacteria required for Bacillus thuringiensis insecticidal activity [J].
Broderick, Nichole A. ;
Raffa, Kenneth F. ;
Handelsman, Jo .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (41) :15196-15199
[2]  
Hardee DD, 2001, ARS154 USDA, P40
[4]   From Commensal to Pathogen: Translocation of Enterococcus faecalis from the Midgut to the Hemocoel of Manduca sexta [J].
Mason, Katie L. ;
Stepien, Taylor A. ;
Blum, Jessamina E. ;
Holt, Jonathan F. ;
Labbe, Normand H. ;
Rush, Jason S. ;
Raffa, Kenneth F. ;
Handelsman, Jo .
MBIO, 2011, 2 (03)
[5]   Insecticidal activity of Bacillus thuringiensis crystal proteins [J].
van Frankenhuyzen, Kees .
JOURNAL OF INVERTEBRATE PATHOLOGY, 2009, 101 (01) :1-16