Type III secretion: More systems than you think

被引:194
作者
Troisfontaines, P [1 ]
Cornelis, GR [1 ]
机构
[1] Univ Basel, Biozentrum, CH-4056 Basel, Switzerland
关键词
D O I
10.1152/physiol.00011.2005
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
The type III secretion (T3S) pathway allows bacteria to inject effector proteins into the cytosol of target animal or plant cells. T3S systems evolved into seven families that were distributed among Gram-negative bacteria by horizontal gene transfer. There are probably a few hundred effectors interfering with control and signaling in eukaryotic cells and offering a wealth of new tools to cell biologists.
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页码:326 / 339
页数:14
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