Expression of cardiac neural crest and heart genes isolated by modified differential display

被引：4

作者：

Martinsen, BJ ^{[1
]}

Groebner, NJ ^{[1
]}

Frasier, AJ ^{[1
]}

Lohr, JL ^{[1
]}

机构：

[1] Univ Minnesota, Sch Med, Dept Pediat, Div Pediat Cardiol, Minneapolis, MN 55455 USA

来源：

GENE EXPRESSION PATTERNS | 2003年 / 3卷 / 04期

关键词：

heart development; congenital heart disease; differential display; neural crest; cardiac neural crest; secondary heart field; cardiac chamber specification; outflow tract septation; cardiac valve formation; chick; notochord; cardiac inflow; linear heart tube; differential expression;

D O I：

10.1016/S1567-133X(03)00088-7

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The invasion of the cardiac neural crest (CNC) into the outflow tract (OFT) and subsequent outflow tract septation are critical events during vertebrate heart development. We have performed four modified differential display screens in the chick embryo to identify genes that may be involved in CNC, OFT, secondary heart field, and heart development. The screens included differential display of RNA isolated from three different axial segments containing premigratory cranial neural crest cells; of RNA from distal outflow tract, proximal outflow tract, and atrioventricular tissue of embryonic chick hearts; and of RNA isolated from left and right cranial tissues, including the early heart fields. These screens have resulted in the identification of the five cDNA clones presented here, which are expressed in the cardiac neural crest, outflow tract and developing heart in patterns that are unique in heart development. (C) 2003 Elsevier Science B.V. All rights reserved.

引用

页码：407 / 411

页数：5

共 23 条

[1] Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors [J].

Camenisch, TD ;

Schroeder, JA ;

Bradley, J ;

Klewer, SE ;

McDonald, JA .

NATURE MEDICINE, 2002, 8 (08) :850-855

[2] Screening from a subtracted embryonic chick hindbrain cDNA library: identification of genes expressed during hindbrain, midbrain and cranial neural crest development [J].

Christiansen, JH ;

Coles, EG ;

Robinson, V ;

Pasini, A ;

Wilkinson, DG .

MECHANISMS OF DEVELOPMENT, 2001, 102 (1-2) :119-133

[3]

Clark EB., 1987, GENETICS CARDIOVASCU, P3

[4] MOLECULAR REGULATION OF ATRIOVENTRICULAR VALVULOSEPTAL MORPHOGENESIS [J].

EISENBERG, LM ;

MARKWALD, RR .

CIRCULATION RESEARCH, 1995, 77 (01) :1-6

[5]

Etchevers HC, 2001, DEVELOPMENT, V128, P1059

[6] Notochord regulates cardiac lineage in zebrafish embryos [J].

Goldstein, AM ;

Fishman, MC .

DEVELOPMENTAL BIOLOGY, 1998, 201 (02) :247-252

[7] A SERIES OF NORMAL STAGES IN THE DEVELOPMENT OF THE CHICK EMBRYO [J].

HAMBURGER, V ;

HAMILTON, HL .

JOURNAL OF MORPHOLOGY, 1951, 88 (01) :49-&

[8] EXPRESSION OF A DELTA-HOMOLOG IN PROSPECTIVE NEURONS IN THE CHICK [J].

HENRIQUE, D ;

ADAM, J ;

MYAT, A ;

CHITNIS, A ;

LEWIS, J ;

ISHHOROWICZ, D .

NATURE, 1995, 375 (6534) :787-790

[9] The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm [J].

Kelly, RG ;

Brown, NA ;

Buckingham, ME .

DEVELOPMENTAL CELL, 2001, 1 (03) :435-440

[10] NEURAL CREST ORIGIN OF CARDIAC GANGLION-CELLS IN THE CHICK-EMBRYO - IDENTIFICATION AND EXTIRPATION [J].

KIRBY, ML ;

STEWART, DE .

DEVELOPMENTAL BIOLOGY, 1983, 97 (02) :433-443

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