An approach to pancratistatin from myo-inositol

被引：30

作者：

Gauthier, DR ^{[1
]}

Bender, SL ^{[1
]}

机构：

[1] UNIV CALIF IRVINE, DEPT CHEM, IRVINE, CA 92717 USA

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 01期

关键词：

D O I：

10.1016/0040-4039(95)02070-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly advanced intermediate (15) for the synthesis of 7-deoxypancratistatin was prepared in 11 steps from myo-inositol. Introduction of the C-10b-Ar bond through an intramolecular epoxide opening with an aryl anion is the key step in this approach.

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页码：13 / 16

页数：4

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