Loop-closure principles in protein folding

被引:20
作者
Weikl, Thomas R. [1 ]
机构
[1] Max Planck Inst Colloids & Interfaces, Dept Theory & Biosyst, D-14424 Potsdam, Germany
关键词
protein folding kinetics; native-state topology; two-state proteins; folding rates; contact order; topological measures; folding routes; loop-closure entropy; effective contact order;
D O I
10.1016/j.abb.2007.06.018
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Simple theoretical concepts and models have been helpful to understand the folding rates and routes of single-domain proteins. As reviewed in this article, a physical principle that appears to underly these models is loop closure. (C) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码:67 / 75
页数:9
相关论文
共 148 条
  • [1] Contour length and refolding rate of a small protein controlled by engineered disulfide bonds
    Ainavarapu, Rama Koti
    Brujic, Jasna
    Huang, Hector H.
    Wiita, Arun P.
    Lu, Hui
    Li, Lewyn
    Walther, Kirstin A.
    Carrion-Vazquez, Mariano
    Li, Hongbin
    Fernandez, Julio M.
    [J]. BIOPHYSICAL JOURNAL, 2007, 92 (01) : 225 - 233
  • [2] Simple physical models connect theory and experiment in protein folding kinetics
    Alm, E
    Morozov, AV
    Kortemme, T
    Baker, D
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2002, 322 (02) : 463 - 476
  • [3] Prediction of protein-folding mechanisms from free-energy landscapes derived from native structures
    Alm, E
    Baker, D
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (20) : 11305 - 11310
  • [4] Fine structure analysis of a protein folding transition state; distinguishing between hydrophobic stabilization and specific packing
    Anil, B
    Sato, S
    Cho, JH
    Raleigh, DP
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2005, 354 (03) : 693 - 705
  • [5] Protein folding pathways studied by pulsed-and native-state hydrogen exchange
    Bai, Yawen
    [J]. CHEMICAL REVIEWS, 2006, 106 (05) : 1757 - 1768
  • [6] PROTEIN-FOLDING INTERMEDIATES - NATIVE-STATE HYDROGEN-EXCHANGE
    BAI, YW
    SOSNICK, TR
    MAYNE, L
    ENGLANDER, SW
    [J]. SCIENCE, 1995, 269 (5221) : 192 - 197
  • [7] A surprising simplicity to protein folding
    Baker, D
    [J]. NATURE, 2000, 405 (6782) : 39 - 42
  • [8] Toward high-resolution de novo structure prediction for small proteins
    Bradley, P
    Misura, KMS
    Baker, D
    [J]. SCIENCE, 2005, 309 (5742) : 1868 - 1871
  • [9] Intermediates and the folding of proteins L and G
    Brown, S
    Head-Gordon, T
    [J]. PROTEIN SCIENCE, 2004, 13 (04) : 958 - 970
  • [10] Exact solution of the Munoz-Eaton model for protein folding
    Bruscolini, P
    Pelizzola, A
    [J]. PHYSICAL REVIEW LETTERS, 2002, 88 (25) : 4