Chemical synthesis of optically active cis-cyclohexa-3,5-diene-1,2-diols and their 5-2H-derivatives

被引：10

作者：

Hanazawa, T ^{[1
]}

Okamoto, S ^{[1
]}

Sato, F ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Biomol Engn, Midori Ku, Yokohama, Kanagawa 2268501, Japan

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 32期

关键词：

cis-cyclohexane-3,5-dien-1,2-diol; optically active; chemical synthesis; deuterium;

D O I：

10.1016/S0040-4039(01)01014-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of optically active 3-substituted cis-cyclohexane-3,5-dien-1,2-diol acetonides were readily prepared from chiral 5-(tert-butyldimethylsilyloxy)-2-cyclohexenone through a seven-step reaction in good overall yield. The synthesis also allowed preparation of the acetonide having an H-2-atom at the 5-position. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：5455 / 5457

页数：3

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