Absolute metabolite quantification by in vivo NMR spectroscopy:: V.: Multicentre quantitative data analysis trial on the overlapping background problem

被引:15
作者
de Beer, R [1 ]
Van den Boogaart, A [1 ]
Cady, E [1 ]
Graveron-Demilly, D [1 ]
Knijn, A [1 ]
Langenberger, KW [1 ]
Lindon, JC [1 ]
Ohlhoff, A [1 ]
Serraî, H [1 ]
Wylezinska-Arridge, M [1 ]
机构
[1] Delft Univ Technol, Dept Appl Phys, NL-2600 GA Delft, Netherlands
关键词
multicentre data-analysis trial; time-domain test signals; overlapping background;
D O I
10.1016/S0730-725X(98)00121-0
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The goal of this study was to establish the best approach for quantifying nuclear magnetic resonance (NMR) lines, that in the frequency domain are overlapping with broad, unwanted background features. To perform the quantitative data analysis in a controlled way, test signals were designed and utilised, derived from two different real-world in vivo nuclear magnetic resonance signals, One of the main conclusions of the study was that the quantification methods currently available to the biomedical research groups can deliver the correct values of the quantitative parameters, but that great care should be taken in using optimal input parameters for the computer programs concerned. (C) 1998 Elsevier Science Inc.
引用
收藏
页码:1127 / 1137
页数:11
相关论文
共 18 条
[1]  
BARHUIJSEN H, 1987, J MAGN RESON, V73, P553
[2]  
BARHUIJSEN H, 1986, J MAGN RESON, V67, P371
[3]   THE WAVELET TRANSFORM FOR PREPROCESSING IR-SPECTRA IN THE IDENTIFICATION OF MONOSUBSTITUTED AND DISUBSTITUTED BENZENES [J].
BOS, M ;
VRIELINK, JAM .
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 1994, 23 (01) :115-122
[4]   BAYESIAN-ANALYSIS .5. AMPLITUDE ESTIMATION FOR MULTIPLE WELL-SEPARATED SINUSOIDS [J].
BRETTHORST, GL .
JOURNAL OF MAGNETIC RESONANCE, 1992, 98 (03) :501-523
[5]   SIGNAL ENHANCEMENT - A COMPOSITE PROPERTY MAPPING ALGORITHM [J].
CADZOW, JA .
IEEE TRANSACTIONS ON ACOUSTICS SPEECH AND SIGNAL PROCESSING, 1988, 36 (01) :49-62
[6]   REDUCED LIPID CONTAMINATION IN IN-VIVO H-1 MRSI USING TIME-DOMAIN FITTING AND NEURAL-NETWORK CLASSIFICATION [J].
DEBEER, R ;
MICHELS, F ;
VANORMONDT, D ;
VANTONGEREN, BPO ;
LUYTEN, PR ;
VANVROONHOVEN, H .
MAGNETIC RESONANCE IMAGING, 1993, 11 (07) :1019-1026
[7]  
DELTRAT N, 1992, IEEE T INFORM THEORY, V38, P644
[8]  
DERICHE M, 1992, 11 ANN SCI M SMRM BE, P4254
[9]   IMPROVEMENTS OF QUANTITATION BY USING THE CADZOW ENHANCEMENT PROCEDURE PRIOR TO ANY LINEAR-PREDICTION METHODS [J].
DIOP, A ;
ZAIMWADGHIRI, Y ;
BRIGUET, A ;
GRAVERONDEMILLY, D .
JOURNAL OF MAGNETIC RESONANCE SERIES B, 1994, 105 (01) :17-24
[10]  
DUMOULIN CL, 1984, B MAGN RESON, V6, P47