Predictors of obstructive sleep apnea-hypopnea treatment outcome

被引:58
作者
Hoekema, A.
Doff, M. H. J.
de Bont, L. G. M.
van der Hoeven, J. H.
Wijkstra, P. J.
Pasma, H. R.
Stegenga, B.
机构
[1] Univ Groningen, Univ Med Ctr Groningen, Dept Oral & Maxillofacial Surg, NL-9700 RB Groningen, Netherlands
[2] Univ Groningen, Univ Med Ctr Groningen, Dept Clin Neurophysiol, NL-9700 RB Groningen, Netherlands
[3] Univ Groningen, Univ Med Ctr Groningen, Dept Home Mech Ventilat, NL-9700 RB Groningen, Netherlands
[4] Med Ctr Leeuwarden, Dept Pulm Dis, Leeuwarden, Netherlands
关键词
sleep apnea syndromes; orthodontic appliances; positive-pressure ventilation; treatment outcome; predictors;
D O I
10.1177/154405910708601208
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Oral appliance therapy is an alternative to continuous positive airway pressure (CPAP) for treating the obstructive sleep apnea-hypopnea syndrome. However, the ability to pre-select suitable candidates for either treatment is limited. The aim of this study was to assess the value of relevant variables that can predict the outcome of oral appliance and CPAP therapy. Fifty-one patients treated with oral appliance therapy and 52 patients treated with CPAP were included. Relevant clinical, polysomnographic, and cephalometric variables were determined at baseline. The predictive value of variables for treatment outcome was evaluated in univariate and multivariate analyses. The outcome of oral appliance therapy was favorable, especially in less obese patients with milder sleep apnea and with certain craniofacial characteristics (mandibular retrognathism in particular). Neither univariate nor multivariate analyses yielded variables that reliably predicted the outcome of CPAP. We conclude that the variables found in this study are valuable for pre-selecting suitable candidates for oral-appliance therapy.
引用
收藏
页码:1181 / 1186
页数:6
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