学术探索
学术期刊
新闻热点
数据分析
智能评审

The brain is hyperexcitable in migraine

被引：207
作者：
Aurora, S. K. [1 ]
Wilkinson, F. [1 ]
机构：
[1] York Univ, Ctr Vis Res, Toronto, ON M3J 2R7, Canada
来源：
CEPHALALGIA | 2007年 / 27卷 / 12期
关键词：
migraine; hyperexcitability; neurophysiology; psychophysics;
D O I：
10.1111/j.1468-2982.2007.01502.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Migraine is a very common disorder occurring in 20% of women and 6% of men. Central neuronal hyperexcitability is proposed to be the putative basis for the physiological disturbances in migraine. Since there are no consistent structural disturbances in migraine, physiological and psychophysical studies have provided insight into the underlying mechanisms. This is a review of the neurophysiological studies which have provided an insight to migraine pathogenesis supporting the theory of hyperexcitability.
引用
收藏
页码：1442 / 1453
页数：12
相关论文
共 144 条
[1]   Interictal cortical excitability in migraine:: A study using transcranial magnetic stimulation of motor and visual cortices [J].
Afra, J ;
Mascia, A ;
Gérard, P ;
de Noordhout, AM ;
Schoenen, J .
ANNALS OF NEUROLOGY, 1998, 44 (02) :209-215
[2]   Visual evoked potentials during long periods of pattern-reversal stimulation in migraine [J].
Afra, J ;
Cecchini, AP ;
De Pasqua, V ;
Albert, A ;
Schoenen, J .
BRAIN, 1998, 121 :233-241
[3]  
Aguggia M, 1999, CEPHALALGIA, V19, P465
[4]   Higher variability of phosphene thresholds in migraineurs than in controls: a consecutive transcranial magnetic stimulation study [J].
Antal, A. ;
Arlt, S. ;
Nitsche, M. A. ;
Chadaide, Z. ;
Paulus, W. .
CEPHALALGIA, 2006, 26 (07) :865-870
[5]   Altered motion perception in migraineurs: evidence for interictal cortical hyperexcitability [J].
Antal, A ;
Temme, J ;
Nitsche, MA ;
Varga, ET ;
Lang, N ;
Paulus, W .
CEPHALALGIA, 2005, 25 (10) :788-794
[6]   Direct current stimulation over MT+/V5 modulates motion aftereffect in humans [J].
Antal, A ;
Varga, ET ;
Nitsche, MA ;
Chadaide, Z ;
Paulus, W ;
Kovács, G ;
Vidnyánszky, Z .
NEUROREPORT, 2004, 15 (16) :2491-2494
[7]   Transcranial magnetic stimulation confirms hyperexcitability of occipital cortex in migraine [J].
Aurora, SK ;
Ahmad, BK ;
Welch, KMA ;
Bhardhwaj, P ;
Ramadan, NM .
NEUROLOGY, 1998, 50 (04) :1111-1114
[8]   The occipital cortex is hyperexcitable in migraine: Experimental evidence [J].
Aurora, SK ;
Cao, Y ;
Bowyer, SM ;
Welch, KMA .
HEADACHE, 1999, 39 (07) :469-476
[9]   Brain excitability in migraine: evidence from transcranial magnetic stimulation studies [J].
Aurora, SK ;
Welch, KMA .
CURRENT OPINION IN NEUROLOGY, 1998, 11 (03) :205-209
[10]   Cortical inhibition is reduced in chronic and episodic migraine and demonstrates a spectrum of illness [J].
Aurora, SK ;
Barrodale, P ;
Chronicle, EP ;
Mulleners, WM .
HEADACHE, 2005, 45 (05) :546-552
12345678910