Ethnic trends in lipid tests in general practice

被引:16
作者
France, MW
Kwok, S
McElduff, P
Seneviratne, CJ
机构
[1] Manchester Royal Infirm, CMMCUH NHS Trust, Dept Clin Biochem, Manchester M13 9WL, Lancs, England
[2] Barlow Med Ctr, Manchester, Lancs, England
[3] Univ Manchester, Dept Epidemiol, Manchester, Lancs, England
关键词
D O I
10.1093/qjmed/hcg154
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: South Asian migrants have a higher cardiovascular mortality than the indigenous population. Contributory factors may include a lower rate of cardiovascular risk assessment uptake and compliance. Aim: To compare rates of lipid testing, follow-up and patterns of dyslipidaemia in South Asian and non-South-Asian populations in Manchester. Design: Retrospective cross-sectional survey. Methods: Lipid requests from 14 general practices were analysed, using name recognition software to assign ethnicity. Results: Compared with non-South-Asians, the age-standardized rate of lipid testing in South Asians was similar in men at 12.1% (95% CI 11.6-12.6) vs. 11.2% (9.5-13.0), but higher in women at 18.6% (15.9-21.2) vs. 13.2% (12.6-13.7). Trends of cholesterol with repeat testing were similar in the two populations. However, South Asian women had lower mean levels of total cholesterol (5.50 vs. 5.68 mmol/l, p= 0.021), lower levels of HDL (1.20 vs. 1.46 mmol/l, p<0.001), an excess of hypertriglyceridaemia (1.62 vs. 1.45 mmol/l, p = 0.035) and a greater proportion with cholesterol >5.2 mmol/l combined with low HDL (43.1% vs. 20.2%, p=0.002). South Asian men had lower levels of total cholesterol (5.17 vs. 5.37 mmol/l, p = 0.048) and lower levels of HDL (1.07 vs. 1.64 mmol/l, p<0.001). There was no difference in the proportion of South Asians men and women with cholesterol <5.2 mmol/l combined with low HDL. Discussion: The rate of lipid testing and change in cholesterol levels with repeated testing did not differ between South Asian and non-South-Asian groups. The pattern of dyslipidaemia seen in this South Asian population, especially women, was different from that of the non-South-Asian population, with possible implications for cardiovascular risk assessment.
引用
收藏
页码:919 / 923
页数:5
相关论文
共 22 条
[1]   Differences in risk factors, atherosclerosis, and cardiovascular disease between ethnic groups in Canada: the Study of Health Assessment and Risk in Ethnic groups (SHARE) [J].
Anand, SS ;
Yusuf, S ;
Vuksan, V ;
Devanesen, S ;
Teo, KK ;
Montague, PA ;
Kelemen, L ;
Yi, CL ;
Lonn, E ;
Gerstein, H ;
Hegele, RA ;
McQueen, M .
LANCET, 2000, 356 (9226) :279-284
[2]   ETHNIC-DIFFERENCES IN MORTALITY FROM ISCHEMIC-HEART-DISEASE AND CEREBROVASCULAR-DISEASE IN ENGLAND AND WALES [J].
BALARAJAN, R .
BMJ-BRITISH MEDICAL JOURNAL, 1991, 302 (6776) :560-564
[3]  
BHATNAGAR D, 1995, LANCET, V345, P405
[4]   Heterogeneity of coronary heart disease risk factors in Indian, Pakistani, Bangladeshi, and European origin populations: cross sectional study [J].
Bhopal, R ;
Unwin, N ;
White, M ;
Yallop, J ;
Walker, L ;
Alberti, KGMM ;
Harland, J ;
Patel, S ;
Ahmad, N ;
Turner, C ;
Watson, B ;
Kaur, D ;
Kulkarni, A ;
Laker, M ;
Tavridou, A .
BRITISH MEDICAL JOURNAL, 1999, 319 (7204) :215-+
[5]   Ethnic and socio-economic inequalities in coronary heart disease, diabetes and risk factors in Europeans and South Asians [J].
Bhopal, R ;
Hayes, L ;
White, M ;
Unwin, N ;
Harland, J ;
Ayis, S ;
Alberti, G .
JOURNAL OF PUBLIC HEALTH MEDICINE, 2002, 24 (02) :95-105
[6]   Ethnicity and cardiovascular risk: variations in people of African ancestry and South Asian origin [J].
Cappuccio, FP .
JOURNAL OF HUMAN HYPERTENSION, 1997, 11 (09) :571-576
[7]   Application of Framingham risk estimates to ethnic minorities in United Kingdom and implications for primary prevention of heart disease in general practice: cross sectional population based study [J].
Cappuccio, FP ;
Oakeshott, P ;
Strazzullo, P ;
Kerry, SM .
BRITISH MEDICAL JOURNAL, 2002, 325 (7375) :1271-1274B
[8]   Prevalence, detection, and management of cardiovascular risk factors in different ethnic groups in south London [J].
Cappuccio, FP ;
Cook, DG ;
Atkinson, RW ;
Strazzullo, P .
HEART, 1997, 78 (06) :555-563
[9]   An assessment of the Nam Pehchan computer program for the identification of names of south Asian ethnic origin [J].
Cummins, C ;
Winter, H ;
Cheng, KK ;
Maric, R ;
Silcocks, P ;
Varghese, C .
JOURNAL OF PUBLIC HEALTH MEDICINE, 1999, 21 (04) :401-406
[10]   Validation of the Framingham Coronary Heart Disease prediction scores - Results of a multiple ethnic groups investigation [J].
D'Agostino, RB ;
Grundy, S ;
Sullivan, LM ;
Wilson, P .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 286 (02) :180-187