Electrochemical studies of rutin interacting with hemoglobin and determination of hemoglobin

被引：115

作者：

Bao, XY ^{[1
]}

Zhu, ZW ^{[1
]}

Li, NQ ^{[1
]}

Chen, JG ^{[1
]}

机构：

[1] Peking Univ, Dept Chem, Beijing 100871, Peoples R China

来源：

TALANTA | 2001年 / 54卷 / 04期

基金：

中国国家自然科学基金;

关键词：

rutin; hemoglobin; supramolecule; cyclic voltammetry;

D O I：

10.1016/S0039-9140(00)00667-6

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Electrochemical investigation of the interaction of rutin (Rt) with hemoglobin (Hb) at a glassy carbon electrode is reported for the first time. With the addition of hemoglobin in a rutin solution, both the reduction and oxidation currents decrease with few changes in the peak potentials. The reaction of rutin with hemoglobin forms a nonelectroactive supramolecular complex Hb-Rt. The equilibrium constant for complex is calculated to be 3.4 x 10(6). A satisfactory result has been obtained for the determination of hemoglobin in clinical blued samples. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：591 / 596

页数：6

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