1-year follow-up of autologous muscle-derived stem cell injection pilot study to treat stress urinary incontinence

被引：223

作者：

Carr, L. K. ^{[3
]}

Steele, D. ^{[3
]}

Steele, S. ^{[3
]}

Wagner, D. ^{[2
]}

Pruchnic, R. ^{[2
]}

Jankowski, R. ^{[2
]}

Erickson, J. ^{[1
]}

Huard, J. ^{[1
]}

Chancellor, M. B. ^{[1
]}

机构：

[1] Univ Pittsburgh, Sch Med, Pittsburgh, PA 15213 USA

[2] Cook Myosite, Pittsburgh, PA 19238 USA

[3] Sunnybrook Hlth Sci Ctr, Toronto, ON M4N 3M5, Canada

来源：

INTERNATIONAL UROGYNECOLOGY JOURNAL | 2008年 / 19卷 / 06期

关键词：

stress urinary incontinence; stem cell; muscle; urethra;

D O I：

10.1007/s00192-007-0553-z

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

We hereby report a 1-year follow-up on eight women in the first North America trial in which stress urinary incontinence (SUI) was treated with muscle-derived stem cell injections. Mean and median follow-up in this group was 16.5 and 17 months (range 3-24 months). Improvement in SUI was seen in five of eight women, with one achieving total continence. Onset of improvement was between 3 and 8 months after injection. Cure or improvement continued at a median of 10 months. No serious adverse events were reported.

引用

收藏

页码：881 / 883

页数：3

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