Perspectives in cholesterol-lowering therapy - The role of ezetimibe, a new selective inhibitor of intestinal cholesterol absorption

被引：68

作者：

Bruckert, E ^{[1
]}

Giral, P ^{[1
]}

Tellier, P ^{[1
]}

机构：

[1] Hop La Pitie Salpetriere, Dept Endocrinol, APHP, Serv Endocrinol Metab, F-75651 Paris 13, France

来源：

CIRCULATION | 2003年 / 107卷 / 25期

关键词：

D O I：

10.1161/01.CIR.0000072345.98581.24

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：3124 / 3128

页数：5

共 20 条

[1] Ezetimibe: efficacy and safety in clinical trials [J].

Ballantyne, CM .

EUROPEAN HEART JOURNAL SUPPLEMENTS, 2002, 4 (0J) :J9-J18

[2] Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: Pooled analysis of two phase II studies [J].

Bays, HE ;

Moore, PB ;

Drehobl, MA ;

Rosenblatt, S ;

Toth, PD ;

Dujovne, CA ;

Knopp, RH ;

Lipka, LJ ;

LeBeaut, AP ;

Yang, B ;

Mellars, LE ;

Cuffie-Jackson, C ;

Veltri, EP .

CLINICAL THERAPEUTICS, 2001, 23 (08) :1209-1230

[3] New advances in lipid-modifying therapies for reducing cardiovascular risk [J].

Bruckert, E .

CARDIOLOGY, 2002, 97 (02) :59-66

[4] Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia [J].

Davidson, MH ;

McGarry, T ;

Bettis, R ;

Melani, L ;

Lipka, LJ ;

LeBeaut, AP ;

Suresh, R ;

Sun, S ;

Veltri, EP .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2002, 40 (12) :2125-2134

[5] A target for cholesterol absorption inhibitors in the enterocyte brush border membrane [J].

Detmers, PA ;

Patel, S ;

Hernandez, M ;

Montenegro, J ;

Lisnock, J ;

Pikounis, B ;

Steiner, M ;

Kim, D ;

Sparrow, C ;

Chao, YS ;

Wright, SD .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2000, 1486 (2-3) :243-252

[6] Statins do not meet expectations for lowering low-density lipoprotein cholesterol levels when used in clinical practice [J].

Frolkis, JP ;

Pearce, GL ;

Nambi, V ;

Minor, S ;

Sprecher, DL .

AMERICAN JOURNAL OF MEDICINE, 2002, 113 (08) :625-629

[7] Efficacy and safety of Ezetimibe added to ongoing statin therapy for treatment of patients with primary hypercholesterolemia [J].

Gagné, C ;

Bays, HÉ ;

Weiss, SR ;

Mata, P ;

Quinto, K ;

Melino, M ;

Cho, M ;

Musliner, TA ;

Gumbiner, B .

AMERICAN JOURNAL OF CARDIOLOGY, 2002, 90 (10) :1084-1091

[8] Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia [J].

Gagné, C ;

Gaudet, D ;

Bruckert, E .

CIRCULATION, 2002, 105 (21) :2469-2475

[9] Comparative dose efficacy study of Atorvastatin versus Simvastatin, Pravastatin, Lovastatin, and Fluvastatin in patients with hypercholesterolemia (The CURVES study) [J].

Jones, P ;

Kafonek, S ;

Laurora, I ;

Hunninghake, D .

AMERICAN JOURNAL OF CARDIOLOGY, 1998, 81 (05) :582-587

[10]

Knopp RH, 2001, ATHEROSCLEROSIS SUPP, V2, P38

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