ADHD and dyscalculia: Evidence for independent familial transmission

被引:38
作者
Monuteaux, MC
Faraone, SV
Herzig, K
Navsaria, N
Biederman, J
机构
[1] Harvard Univ, Sch Med, Cambridge, MA 02138 USA
[2] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA
[3] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat, Cambridge, MA 02138 USA
[4] Brown Univ, Ctr Alcohol & Addict Studies, Providence, RI 02912 USA
[5] Massachusetts Gen Hosp, Pediat Psychopharmacol Program, Boston, MA 02114 USA
[6] Massachusetts Gen Hosp, Adult ADHD Program, Boston, MA 02114 USA
关键词
D O I
10.1177/00222194050380010701
中图分类号
G76 [特殊教育];
学科分类号
040109 ;
摘要
The familial relationship between dyscalculia and attention-deficit/hyperactivity disorder (ADHD) was assessed. We conducted a familial risk analysis using probands with and without ADHD of both genders and their first-degree relatives. Participants were assessed with structured diagnostic interviews and a cognitive test battery. We found elevated rates of ADHD in relatives of both ADHD proband groups, regardless of dyscalculia status, and elevated rates of dyscalculia in relatives of probands with dyscalculia, irrespective of ADHD status. There was no evidence for cosegregation or assortative mating. Our findings support the hypothesis that ADHD and dyscalculia are independently transmitted in families and are etiologically distinct. These results reinforce the current nosological approach to these disorders and underscore the need for separate identification and treatment strategies for children with both conditions.
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页码:86 / 93
页数:8
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