Characterization of a 34-kilodalton protein of Mycobacterium leprae that is isologous to the immunodominant 34-kilodalton antigen of Mycobacterium paratuberculosis

被引：13

作者：

Silbaq, FS

Cho, SN

Cole, ST

Brennan, PJ ^{[1
]}

机构：

[1] Colorado State Univ, Dept Microbiol, Ft Collins, CO 80523 USA

[2] Inst Pasteur, Paris, France

[3] Yonsei Univ, Coll Med, Dept Microbiol, Seoul, South Korea

来源：

INFECTION AND IMMUNITY | 1998年 / 66卷 / 11期

关键词：

D O I：

10.1128/IAI.66.11.5576-5579.1998

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During DNA sequence analysis of cosmid L373 from the Mycobacterium leprae genome, an open reading frame of 1.4 kb encoding a protein with some homology to the immunodominant 34-kDa protein of Mycobacterium paratuberculosis, but lacking significant serological activity, was detected. The DNA sequence predicted a signal peptide with a modified lipoprotein consensus sequence, but the protein proved to be devoid of lipid attachment.

引用

页码：5576 / 5579

页数：4

共 21 条

[1] ISSUES IN SEARCHING MOLECULAR SEQUENCE DATABASES [J].