Adipose tissue hormones and the regulation of food intake

被引:64
作者
Henry, B. A. [1 ]
Clarke, I. J. [1 ]
机构
[1] Monash Univ, Dept Physiol, Clayton, Vic 3800, Australia
关键词
leptin; hypothalamus; food intake and energy expenditure;
D O I
10.1111/j.1365-2826.2008.1730.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Over the past decade, adipose tissue has been shown to produce numerous factors that act as hormones. Many of these act on the brain to regulate energy balance via dual effects on food intake and energy expenditure. These include well-characterised hormones such as leptin, oestrogen and glucocorticoids and novel factors such as adiponectin and resistin. This review provides a perspective on the role of these factors as lipostats.
引用
收藏
页码:842 / 849
页数:8
相关论文
共 87 条
[1]   Stress, eating and the reward system [J].
Adam, Tanja C. ;
Epel, Elissa S. .
PHYSIOLOGY & BEHAVIOR, 2007, 91 (04) :449-458
[2]   Metabolic actions of adipocyte hormones: Focus on adiponectin [J].
Ahima, Rexford S. .
OBESITY, 2006, 14 :9S-15S
[3]   Role of leptin in the neuroendocrine response to fasting [J].
Ahima, RS ;
Prabakaran, D ;
Mantzoros, C ;
Qu, DQ ;
Lowell, B ;
MaratosFlier, E ;
Flier, JS .
NATURE, 1996, 382 (6588) :250-252
[4]   Leptin receptor signaling in is required for normal body POW neurons weight homeostasis [J].
Balthasar, N ;
Coppari, R ;
McMinn, J ;
Liu, SM ;
Lee, CE ;
Tang, V ;
Kenny, CD ;
McGovern, RA ;
Chua, SC ;
Elmquist, JK ;
Lowell, BB .
NEURON, 2004, 42 (06) :983-991
[5]   Regulation of fasted blood glucose by resistin [J].
Banerjee, RR ;
Rangwala, SM ;
Shapiro, JS ;
Rich, AS ;
Rhoades, B ;
Qi, Y ;
Wang, J ;
Rajala, MW ;
Pocai, A ;
Scherer, PE ;
Steppan, CM ;
Ahima, RS ;
Obici, S ;
Rossetti, L ;
Lazar, MA .
SCIENCE, 2004, 303 (5661) :1195-1198
[6]   The effects of high fat diets on the blood-brain barrier transport of leptin: Failure or adaptation? [J].
Banks, William A. ;
Farr, Susan A. ;
Morley, John E. .
PHYSIOLOGY & BEHAVIOR, 2006, 88 (03) :244-248
[7]   Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome [J].
Bingham, Nathan C. ;
Anderson, Kimberly K. ;
Reuter, Anne L. ;
Stallings, Nancy R. ;
Parker, Keith L. .
ENDOCRINOLOGY, 2008, 149 (05) :2138-2148
[8]   Identification of SOCS-3 as a potential mediator of central leptin resistance [J].
Bjorbaek, C ;
Elmquist, JK ;
Frantz, JD ;
Shoelson, SE ;
Flier, JS .
MOLECULAR CELL, 1998, 1 (04) :619-625
[9]   The role of SOCS-3 in leptin signaling and leptin resistance [J].
Bjorbæk, C ;
El-Haschimi, K ;
Frantz, JD ;
Flier, JS .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (42) :30059-30065
[10]   Opposing effects of adiponectin receptors 1 and 2 on energy metabolism [J].
Bjursell, Mikael ;
Ahnmark, Andrea ;
Bohlooly-Y, Mohammad ;
William-Olsson, Lena ;
Rhedin, Magdalena ;
Peng, Xiao-Rong ;
Ploj, Karolina ;
Gerdin, Anna-Karin ;
Arnerup, Gunnel ;
Elmgren, Anders ;
Berg, Anna-Lena ;
Oscarsson, Jan ;
Linden, Daniel .
DIABETES, 2007, 56 (03) :583-593