Assessment of cutaneous innervation by skin biopsies

被引：50

作者：

Griffin, JW ^{[1
]}

McArthur, JC ^{[1
]}

Polydefkis, M ^{[1
]}

机构：

[1] Johns Hopkins Univ Hosp, Baltimore, MD 21187 USA

来源：

CURRENT OPINION IN NEUROLOGY | 2001年 / 14卷 / 05期

关键词：

D O I：

10.1097/00019052-200110000-00016

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Skin biopsies that are immunostained to identify nerve fibers provide a new tool for assessing the small caliber nociceptors that terminate in the epidermis, as well as other cutaneous nerve fibers. Skin biopsies can be performed in multiple sites and can be repeated over time, so that a spatiotemporal profile of epidermal innervation can be constructed. This approach may help assess the progression of fiber loss in disease and of regeneration and re-innervation. with treatment. Curr Opin Neurol 14:655-659. (C) 2001 Lippincott Williams & Wilkins.

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页码：655 / 659

页数：5

相关论文

共 54 条

[1] Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons [J].

Black, JA ;

Cummins, TR ;

Plumpton, C ;

Chen, YH ;

Hormuzdiar, W ;

Clare, JJ ;

Waxman, SG .

JOURNAL OF NEUROPHYSIOLOGY, 1999, 82 (05) :2776-2785

[2] Impaired nociception and pain sensation in mice lacking the capsaicin receptor [J].

Caterina, MJ ;

Leffler, A ;

Malmberg, AB ;

Martin, WJ ;

Trafton, J ;

Petersen-Zeitz, KR ;

Koltzenburg, M ;

Basbaum, AI ;

Julius, D .

SCIENCE, 2000, 288 (5464) :306-313

[3] A capsaicin-receptor homologue with a high threshold for noxious heat [J].

Caterina, MJ ;

Rosen, TA ;

Tominaga, M ;

Brake, AJ ;

Julius, D .

NATURE, 1999, 398 (6726) :436-441

[4] PREDOMINANTLY SENSORY NEUROPATHY IN PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX [J].

CORNBLATH, DR ;

MCARTHUR, JC .

NEUROLOGY, 1988, 38 (05) :794-796

[5]

Cummins TR, 1997, J NEUROSCI, V17, P3503

[6] A new combined Bodian-Luxol technique for staining unmyelinated axons in semithin, resin-embedded peripheral nerves: a comparison with electron microscopy [J].

Deprez, M ;

Ceuterick-de Groote, C ;

Fumal, A ;

Reznik, M ;

Martin, JJ .

ACTA NEUROPATHOLOGICA, 1999, 98 (04) :323-329

[7]

Devor M., 1999, TXB PAIN, V4th, P129

[8] THE ROCHESTER DIABETIC NEUROPATHY STUDY - REASSESSMENT OF TESTS AND CRITERIA FOR DIAGNOSIS AND STAGED SEVERITY [J].

DYCK, PJ ;

KARNES, JL ;

OBRIEN, PC ;

LITCHY, WJ ;

LOW, PA ;

MELTON, LJ .

NEUROLOGY, 1992, 42 (06) :1164-1170

[9] THE ROCHESTER DIABETIC NEUROPATHY STUDY - DESIGN, CRITERIA FOR TYPES OF NEUROPATHY, SELECTION BIAS, AND REPRODUCIBILITY OF NEUROPATHIC TESTS [J].

DYCK, PJ ;

KRATZ, KM ;

LEHMAN, KA ;

KARNES, JL ;

MELTON, LJ ;

OBRIEN, PC ;

LITCHY, WJ ;

WINDEBANK, AJ ;

SMITH, BE ;

LOW, PA ;

SERVICE, FJ ;

RIZZA, RA ;

ZIMMERMAN, BR .

NEUROLOGY, 1991, 41 (06) :799-807

[10] Epidermal nerve fiber density and sural nerve morphometry in peripheral neuropathies [J].

Herrmann, DN ;

Griffin, JW ;

Hauer, P ;

Cornblath, DR ;

McArthur, JC .

NEUROLOGY, 1999, 53 (08) :1634-1640

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