Prevalence and genotypes identification of human papillomavirus infection in a population of South Italy

被引：31

作者：

Del Prete, Raffaele ^{[1
]}

Di Taranto, Anna Maria ^{[2
]}

Lipsi, Maria Rosaria ^{[2
]}

Nirchio, Vincenzo ^{[2
]}

Antonetti, Raffaele ^{[2
]}

Miragliotta, Giuseppe ^{[1
]}

机构：

[1] Univ Bari, Microbiol Sect, Dept Clin Med Immunol Infect Dis, I-70124 Bari, Italy

[2] Osped Riuniti OO RR Foggia, I-71100 Foggia, Italy

来源：

JOURNAL OF CLINICAL VIROLOGY | 2008年 / 42卷 / 02期

关键词：

HPV infection; cervical cancer; HPV prevalence; age;

D O I：

10.1016/j.jcv.2008.01.011

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Background: A limited number of human papillomavirus (HPV) types account for the majority of invasive cervical cancer cases. Objectives: To assess, in a southern Italian region, where HPV infection had not yet been investigated, the prevalence of type-specific HPV infection. Study design: Multiplex PCR was used to test cervical specimens from 871 asymptomatic women. Results: The HPV infection rate was 23.1%, with the highest prevalence being observed in women aged 20-30 years (32.6%). Type 16 was the most frequent HPV type detected either in mono-infected (39.8%) or in multi-infected (46.3%) women. Conclusions: The HPV infection rate was higher than reported from other Italian areas. Our results further emphasise the importance of vaccinations to immunize females before they acquire HPV infection. (c) 2008 Elsevier B.V. All rights reserved.

引用

页码：211 / 214

页数：4

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