Pharmacologic versus flow-mediated assessments of peripheral vascular endothelial vasodilatory function in humans

被引：55

作者：

Eskurza, I

Seals, DR

DeSouza, CA

Tanaka, H ^{[1
]}

机构：

[1] Univ Colorado, Dept Kinesiol & Appl Physiol, Human Cardiovasc Res Lab, Boulder, CO 80309 USA

[2] Univ Colorado, Hlth Sci Ctr, Dept Med, Div Cardiol, Denver, CO 80262 USA

[3] Univ Colorado, Hlth Sci Ctr, Dept Med, Div Geriatr Med, Denver, CO 80262 USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2001年 / 88卷 / 09期

关键词：

D O I：

10.1016/S0002-9149(01)01997-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In humans, peripheral vascular endothelial vasodilatory function often is studied by measuring the limb blood flow response to stimulation of nitric oxide release via either intrabrachial artery infusions of acetylcholine or flow-induced brachial artery vasodilation. We conclude that these 2 experimental approaches do not provide the same information on peripheral vascular endothelial vasodilatory function in healthy humans.

引用

页码：1067 / +

页数：4

共 21 条

[1] CLOSE RELATION OF ENDOTHELIAL FUNCTION IN THE HUMAN CORONARY AND PERIPHERAL CIRCULATIONS
ANDERSON, TJ
UEHATA, A
GERHARD, MD
MEREDITH, IT
KNAB, S
DELAGRANGE, D
LIEBERMAN, EH
GANZ, P
CREAGER, MA
YEUNG, AC
SELWYN, AP
[J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1995, 26 (05) : 1235 - 1241
[2] Assessment and treatment of endothelial dysfunction in humans
Anderson, TJ
[J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1999, 34 (03) : 631 - 638
[3] NONINVASIVE DETECTION OF ENDOTHELIAL DYSFUNCTION IN CHILDREN AND ADULTS AT RISK OF ATHEROSCLEROSIS
CELERMAJER, DS
SORENSEN, KE
GOOCH, VM
SPIEGELHALTER, DJ
MILLER, OI
SULLIVAN, ID
LLOYD, JK
DEANFIELD, JE
[J]. LANCET, 1992, 340 (8828) : 1111 - 1115
[4] ENDOTHELIUM-DEPENDENT DILATION IN THE SYSTEMIC ARTERIES OF ASYMPTOMATIC SUBJECTS RELATES TO CORONARY RISK-FACTORS AND THEIR INTERACTION
CELERMAJER, DS
SORENSEN, KE
BULL, C
ROBINSON, J
DEANFIELD, JE
[J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1994, 24 (06) : 1468 - 1474
[5] AGING IS ASSOCIATED WITH ENDOTHELIAL DYSFUNCTION IN HEALTHY-MEN YEARS BEFORE THE AGE-RELATED DECLINE IN WOMEN
CELERMAJER, DS
SORENSEN, KE
SPIEGELHALTER, DJ
GEORGAKOPOULOS, D
ROBINSON, J
DEANFIELD, JE
[J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1994, 24 (02) : 471 - 476
[6] Augmented cardiopulmonary and integrative sympathetic baroreflexes but attenuated peripheral vasoconstriction with age
Davy, KP
Seals, DR
Tanaka, H
[J]. HYPERTENSION, 1998, 32 (02) : 298 - 304
[7] Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men
DeSouza, CA
Shapiro, LF
Clevenger, CM
Dinenno, FA
Monahan, KD
Tanaka, H
Seals, DR
[J]. CIRCULATION, 2000, 102 (12) : 1351 - 1357
[8] Limb blood flow and vascular conductance are reduced with age in healthy humans - Relation to elevations in sympathetic nerve activity and declines in oxygen demand
Dinenno, FA
Jones, PP
Seals, DR
Tanaka, H
[J]. CIRCULATION, 1999, 100 (02) : 164 - 170
[9] Estradiol therapy combined with progesterone and endothelium-dependent vasodilation in postmenopausal women
Gerhard, M
Walsh, BW
Tawakol, A
Haley, EA
Creager, SJ
Seely, EW
Ganz, P
Creager, MA
[J]. CIRCULATION, 1998, 98 (12) : 1158 - 1163
[10] EDRF COORDINATES THE BEHAVIOR OF VASCULAR-RESISTANCE VESSELS
GRIFFITH, TM
EDWARDS, DH
DAVIES, RL
HARRISON, TJ
EVANS, KT
[J]. NATURE, 1987, 329 (6138) : 442 - 445

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