Traffic, outdoor air pollution, and asthma

被引:63
作者
Holguin, Fernando [1 ]
机构
[1] Emory Univ, Sch Med, Div Pulm Allergy & Crit Care, Clin Res Ctr, Atlanta, GA 30308 USA
关键词
D O I
10.1016/j.iac.2008.03.008
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
The epidemiology of asthma and outdoor air pollution has shown that respiratory health effects can vary in relation to different emission sources, types of pollutants, underlying nutritional status, medication use, and genetic polymorphisms. Using sophisticated exposure assessment methods in conjunction with clinical tests and biomarkers that provide mechanistic information, the study of outdoor epidemiology and asthma has evolved into a complex multidisciplinary field. This article presents an overview of the mechanisms by which outdoor air pollution and traffic-related emissions lead to changes in respiratory health and lung function in subjects with asthma.
引用
收藏
页码:577 / +
页数:14
相关论文
共 66 条
[1]   Lung function and long term exposure to air pollutants in Switzerland [J].
AckermannLiebrich, U ;
Leuenberger, P ;
Schwartz, J ;
Schindler, C ;
Monn, C ;
Bolognini, C ;
Bongard, JP ;
Brandli, O ;
Domenighetti, G ;
Elsasser, S ;
Grize, L ;
Karrer, W ;
Keller, R ;
KellerWossidlo, H ;
Kunzli, N ;
Martin, BW ;
Medici, TC ;
Perruchoud, AP ;
Schoni, MH ;
Tschopp, JM ;
Villiger, B ;
Wuthrich, B ;
Zellweger, JP ;
Zemp, E .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1997, 155 (01) :122-129
[2]   OZONE-INDUCED AIRWAY INFLAMMATION IN HUMAN-SUBJECTS AS DETERMINED BY AIRWAY LAVAGE AND BIOPSY [J].
ARIS, RM ;
CHRISTIAN, D ;
HEARNE, PQ ;
KERR, K ;
FINKBEINER, WE ;
BALMES, JR .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1993, 148 (05) :1363-1372
[3]   Respiratory effects of relocating to areas of differing air pollution levels [J].
Avol, EL ;
Gauderman, WJ ;
Tan, SM ;
London, SJ ;
Peters, JM .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 164 (11) :2067-2072
[4]   SYMPTOMATIC BRONCHOCONSTRICTION AFTER SHORT-TERM INHALATION OF SULFUR-DIOXIDE [J].
BALMES, JR ;
FINE, JM ;
SHEPPARD, D .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1987, 136 (05) :1117-1121
[5]   Urban background particulate matter and allergic sensitization in adults of ECRHS II [J].
Bedada, Getahun Bero ;
Heinrich, Joachim ;
Gotschi, Thomas ;
Downs, Sara H. ;
Forsberg, Bertil ;
Jarvis, Deborah ;
Luczynska, Christina ;
Soon, Argo ;
Sunyer, Jordi ;
Toren, Kjell ;
Kunzli, Nino .
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2007, 210 (06) :691-700
[6]   Road traffic and adverse respiratory effects in children [J].
Ciccone, G ;
Forastiere, F ;
Agabiti, N ;
Biggeri, A ;
Bisanti, L ;
Chellini, E ;
Corbo, G ;
Dell'Orco, V ;
Dalmasso, P ;
Volante, TF ;
Galassi, C ;
Piffer, S ;
Renzoni, E ;
Rusconi, F ;
Sestini, P ;
Viegi, G .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 1998, 55 (11) :771-778
[7]  
DEFFINO RJ, 2004, ENV HLTH PERSPECT, V112, P932
[8]   Personal and ambient air pollution is associated with increased exhaled nitric oxide in children with asthma [J].
Delfino, Ralph J. ;
Staimer, Norbert ;
Gillen, Dan ;
Tjoa, Thomas ;
Sioutas, Constantinos ;
Fung, Kochy ;
George, Steven C. ;
Kleinman, Michael T. .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2006, 114 (11) :1736-1743
[9]  
DiazSanchez D, 1997, ALLERGY, V52, P52
[10]  
DiazSanchez D, 1997, J IMMUNOL, V158, P2406