Heart valvular disease in patients with Parkinson's disease treated with high-dose pergolide

被引:101
作者
Van Camp, G
Flamez, A
Cosyns, B
Goldstein, J
Perdaens, C
Schoors, D
机构
[1] Free Univ Brussels, Akad Ziekenhuis, Dept Cardiol, B-1090 Brussels, Belgium
[2] Free Univ Brussels, Dept Neurol, B-1090 Brussels, Belgium
[3] Free Univ Brussels, Dept Cardiac Surg, B-1090 Brussels, Belgium
[4] Free Univ Brussels, Dept Pathol, B-1090 Brussels, Belgium
关键词
D O I
10.1212/01.WNL.0000083985.00343.F2
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors report the clinical, echocardiographic, and pathologic findings in two patients treated with more than 5 mg of pergolide daily who developed symptomatic severe heart failure due to restrictive valvular disease. They also describe the echocardiographic data of another eight patients taking similar doses of pergolide presenting no clinical signs of heart failure. The findings suggest a possible role of high doses of pergolide in inducing restrictive valvular disease.
引用
收藏
页码:859 / 861
页数:3
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