Mitotic kinases as regulators of cell division and its checkpoints

被引:1261
作者
Nigg, EA [1 ]
机构
[1] Max Planck Inst Biochem, Dept Cell Biol, D-82152 Martinsried, Germany
关键词
D O I
10.1038/35048096
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Mitosis and cytokinesis are undoubtedly the most spectacular parts of the cell cycle. Errors in the choreography of these processes can lead to aneuploidy or genetic instability, fostering cell death or disease. Here, I give an overview of the many mitotic kinases that regulate cell division and the fidelity of chromosome transmission.
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页码:21 / 32
页数:12
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共 116 条
  • [1] CENP-E as an essential component of the mitotic checkpoint in vitro
    Abrieu, A
    Kahana, JA
    Wood, KW
    Cleveland, DW
    [J]. CELL, 2000, 102 (06) : 817 - 826
  • [2] Abrieu A, 1998, J CELL SCI, V111, P1751
  • [3] A REVIEW OF THE STAINLESS-STEEL SURFACE
    ADAMS, RO
    [J]. JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A-VACUUM SURFACES AND FILMS, 1983, 1 (01): : 12 - 18
  • [4] INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow
    Adams, RR
    Wheatley, SP
    Gouldsworthy, AM
    Kandels-Lewis, SE
    Carmena, M
    Smythe, C
    Gerloff, DL
    Earnshaw, WD
    [J]. CURRENT BIOLOGY, 2000, 10 (17) : 1075 - 1078
  • [5] Mitotic chromatin regulates phosphorylation of Stathmin/Op18
    Andersen, SSL
    Ashford, AJ
    Tournebize, R
    Gavet, O
    Sobel, A
    Hyman, AA
    Karsenti, E
    [J]. NATURE, 1997, 389 (6651) : 640 - 643
  • [6] Andersen SSL, 1999, BIOESSAYS, V21, P53, DOI 10.1002/(SICI)1521-1878(199901)21:1<53::AID-BIES7>3.3.CO
  • [7] 2-C
  • [8] The kinase Eg2 is a component of the Xenopus oocyte progesterone-activated signaling pathway
    Andrésson, T
    Ruderman, JV
    [J]. EMBO JOURNAL, 1998, 17 (19) : 5627 - 5637
  • [9] GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes
    Arnaud, L
    Pines, J
    Nigg, EA
    [J]. CHROMOSOMA, 1998, 107 (6-7) : 424 - 429
  • [10] Abnormal spindle protein, asp, and the integrity of mitotic centrosomal microtubule organizing centers
    Avides, MD
    Glover, DM
    [J]. SCIENCE, 1999, 283 (5408) : 1733 - 1735