Diagnosis of Ventilator-Associated Respiratory Infections (VARI): Microbiologic Clues for Tracheobronchitis (VAT) and Pneumonia (VAP)

被引：51

作者：

Craven, Donald E. ^{[1
,2
]}

Hudcova, Jana ^{[2
,3
]}

Lei, Yuxiu ^{[1
]}

机构：

[1] Lahey Clin Med Ctr, Ctr Infect Dis & Prevent, Burlington, MA 01805 USA

[2] Tufts Univ, Sch Med, Boston, MA 02110 USA

[3] Lahey Clin Med Ctr, Dept Crit Care & Surg, Burlington, MA 01805 USA

来源：

CLINICS IN CHEST MEDICINE | 2011年 / 32卷 / 03期

关键词：

Ventilator-associated pneumonia; Ventilator-associated tracheobronchitis; Ventilator-associated respiratory infection; Microbiologic criteria for diagnosis; Endotracheal aspirates; Bronchoalveolar lavage antibiotics; Multidrug-resistant bacteria; NOSOCOMIAL TRACHEOBRONCHITIS; MECHANICAL VENTILATION; IMPACT; CARE; SURVEILLANCE; GUIDELINES; MANAGEMENT; RESOLUTION; ACCURACY; CRITERIA;

D O I：

10.1016/j.ccm.2011.06.001

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

100201 [内科学];

摘要：

Intubated patients are at risk of bacterial colonization and ventilator-associated respiratory infection (VARI). VARI includes tracheobronchitis (VAT) or pneumonia (VAP). VAT and VAP caused by multidrug-resistant (MDR) pathogens are increasing in the United States and Europe. In patients with risk factors for MDR pathogens, empiric antibiotics are often initiated for 48 to 72 hours pending the availability of pathogen identification and antibiotic sensitivity data. Extensive data indicate that early, appropriate antibiotic therapy improves outcomes for patients with VAP. Recognizing and treating VARI may allow earlier appropriate therapy and improved patient outcomes.

引用

页码：547 / +

页数：12

共 43 条

[1]

MICROBIOLOGICAL LUNG SURVEILLANCE IN MECHANICALLY VENTILATED PATIENTS, USING NON-DIRECTED BRONCHIAL LAVAGE AND QUANTITATIVE CULTURE [J].

ACOURT, CHD ;

GARRARD, CS ;

CROOK, D ;

BOWLER, I ;

CONLON, C ;

PETO, T ;

ANDERSON, E .

QUARTERLY JOURNAL OF MEDICINE, 1993, 86 (10) :635-648

[2]

Pathophysiology of pneumonia [J].

Alcón, A ;

Fábregas, N ;

Torres, A .

CLINICS IN CHEST MEDICINE, 2005, 26 (01) :39-+

[3]

Guidelines for the management, of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia [J].

不详 .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2005, 171 (04) :388-416

[4]

Protected bronchoalveolar lavage in the diagnosis of ventilator-associated pneumonia [J].

Barreiro, B ;

Dorca, J ;

Manresa, F ;

Catala, I ;

Esteban, L ;

Verdaguer, R ;

Gudiol, F .

EUROPEAN RESPIRATORY JOURNAL, 1996, 9 (07) :1500-1507

[5]

Bauer T T, 2002, Monaldi Arch Chest Dis, V57, P84

[6]

Ventilator-associated pneumonia [J].

Chastre, J ;

Fagon, JY .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 165 (07) :867-903

[7]

Preventing ventilator-associated pneumonia in adults - Sowing seeds of change [J].

Craven, Donald E. .

CHEST, 2006, 130 (01) :251-260

[8]

Ventilator-Associated Tracheobronchitis and Pneumonia: Thinking Outside the Box [J].

Craven, Donald E. ;

Hjalmarson, Karin I. .

CLINICAL INFECTIOUS DISEASES, 2010, 51 :S59-S66

[9]

Ventilator-associated tracheobronchitis (VAT): questions, answers, and a new paradigm? [J].

Craven, Donald E. .

CRITICAL CARE, 2008, 12 (03)

[10]

Ventilator-Associated Tracheobronchitis The Impact of Targeted Antibiotic Therapy on Patient Outcomes [J].

Craven, Donald E. ;

Chroneou, Alexandra ;

Zias, Nikolaos ;

Hjalmarson, Karin I. .

CHEST, 2009, 135 (02) :521-528

← 1 2 3 4 5 →