Nano- and micropatterning of optically transparent, mechanically robust, biocompatible silk fibroin films

被引:164
作者
Perry, Hannih [1 ]
Gopinath, Ashwin [2 ]
Kaplan, David L. [1 ]
Dal Negro, Luca [2 ]
Omenetto, Fiorenzo G. [1 ]
机构
[1] Tufts Univ, Dept Biomed Engn, Medford, MA 02155 USA
[2] Boston Univ, Dept Elect & Comp Engn, Boston, MA 02215 USA
关键词
Biocompatibility;
D O I
10.1002/adma.200800011
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Regular nanometer-scale patterning down to a few tens of nanometers and the manufacturing of diffractive optical elements in silk by using the ideas of soft lithography is reported. The unique processing of silk films makes them an ideal substrate to incorporate biological matter (such as small organics, enzymes, proteins, cells). Unprecedented definition in the transverse direction, with features down to few tens of nanometers, is reported.
引用
收藏
页码:3070 / 3072
页数:3
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