Expanded chemistry of formamidine ureas

被引：21

作者：

Díaz, DD

Finn, MG

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 01期

关键词：

D O I：

10.1021/ol035995f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Formamidine ureas display a rich manifold of reactivity. Thiols induce substitution at the carbonyl carbon to give thiolcarbamates; base-mediated alkylation and acylation occurs at the terminal urea nitrogen, and a new fragmentation/acylation pathway has been uncovered with isocyanates.

引用

收藏

页码：43 / 46

页数：4

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