Primary and secondary prevention of stroke by antihypertensive treatment in clinical trials

被引：11

作者：

Grassi, Guido ^{[1
]}

Arenare, Francesca ^{[1
]}

Trevano, Fosca Quarti ^{[1
]}

Dell'Oro, Raffaella ^{[1
]}

Mancia, Giuseppe ^{[1
]}

机构：

[1] Univ Milan, Osped S Gerardo, Med Clin, I-20052 Monza, Italy

来源：

CURRENT HYPERTENSION REPORTS | 2007年 / 9卷 / 04期

关键词：

D O I：

10.1007/s11906-007-0055-x

中图分类号：

R6 [外科学];

学科分类号：

1002 [临床医学]; 100210 [外科学];

摘要：

High blood pressure represents one of the leading risk factors for the development of stroke and its recurrence. This explains why blood pressure control is a major objective or anti hypertensive treatment, both in primary and secondary prevention of this cerebrovascular disease. This paper reviews the evidence provided by randomized clinical trials on the favorable effects exerted by blood pressure reduction on this end point. Emphasis is given to the results of recently published clinical trials documenting that drugs acting on the renin-angiotensin system may exert cerebrovascular protective effects additive to the ones associated with blood pressure reduction.

引用

页码：299 / 304

页数：6

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