Moving primate genomics beyond the chimpanzee genome

被引：70

作者：

Goodman, M

Grossman, LI

Wildman, DE

机构：

[1] Wayne State Univ, Sch Med, Dept Anat & Cell Biol, Detroit, MI 48201 USA

[2] Wayne State Univ, Sch Med, Ctr Mol Med & Genet, Detroit, MI 48201 USA

[3] NICHHD, Serv Support Perinatol Res Branch, NIH, DHHS, Detroit, MI 48201 USA

来源：

TRENDS IN GENETICS | 2005年 / 21卷 / 09期

关键词：

D O I：

10.1016/j.tig.2005.06.012

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The comparative DNA sequence data that already exist on individual genomic loci depict the phylogenetic relationships of nearly all extant primate genera. Such a phylogenetic representation of the primates, validated by many sequenced primate genomes, and encompassing the full adaptive diversity of the order, is a prerequisite for identifying the genetic basis of humankind, and for testing the proposed human uniqueness of these traits. Some of these traits have been discovered recently, particularly in genes encoding proteins that are important for brain function.

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页码：511 / 517

页数：7

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