Genome sequencing - The worm revealed

被引:5
作者
Chalfie, M [1 ]
机构
[1] Columbia Univ, Dept Biol Sci, New York, NY 10027 USA
关键词
D O I
10.1038/25228
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The genome sequence of the nematode wormCaenorhabditis elegansis now "essentially complete", and this achievement is marked by the publication of a series of papers. At 97 mega base-pairs, corresponding to 19,099 predicted genes, this is the biggest genome yet sequenced, and the first genome sequence for a multicellular organism.
引用
收藏
页码:620 / 621
页数:2
相关论文
共 7 条
[1]   Neurobiology of the Caenorhabditis elegans genome [J].
Bargmann, CI .
SCIENCE, 1998, 282 (5396) :2028-2033
[2]   Caenorhabditis elegans is a nematode [J].
Blaxter, M .
SCIENCE, 1998, 282 (5396) :2041-2046
[3]   Genome sequence of the nematode C-elegans:: A platform for investigating biology [J].
不详 .
SCIENCE, 1998, 282 (5396) :2012-2018
[4]   Comparison of the complete protein sets of worm and yeast: Orthology and divergence [J].
Chervitz, SA ;
Aravind, L ;
Sherlock, G ;
Ball, CA ;
Koonin, EV ;
Dwight, SS ;
Harris, MA ;
Dolinski, K ;
Mohr, S ;
Smith, T ;
Weng, S ;
Cherry, JM ;
Botstein, D .
SCIENCE, 1998, 282 (5396) :2022-2028
[5]   Zinc fingers in Caenorhabditis elegans:: Finding families and probing pathways [J].
Clarke, ND ;
Berg, JM .
SCIENCE, 1998, 282 (5396) :2018-2022
[6]   Life with 6000 genes [J].
Goffeau, A ;
Barrell, BG ;
Bussey, H ;
Davis, RW ;
Dujon, B ;
Feldmann, H ;
Galibert, F ;
Hoheisel, JD ;
Jacq, C ;
Johnston, M ;
Louis, EJ ;
Mewes, HW ;
Murakami, Y ;
Philippsen, P ;
Tettelin, H ;
Oliver, SG .
SCIENCE, 1996, 274 (5287) :546-&
[7]   The taxonomy of developmental control in Caenorhabditis elegans [J].
Ruvkun, G ;
Hobert, O .
SCIENCE, 1998, 282 (5396) :2033-2041