Characterization of early developments in the splenic leukocyte transcriptome of NOD mice

被引：5

作者：

Gerling, IC

Ali, C

Lenchik, N

机构：

[1] Univ Tennessee, Hlth Sci Ctr, VAMC, Dept Med, Memphis, TN 38104 USA

[2] Vet Affairs Med Ctr, Res Serv, Memphis, TN USA

来源：

IMMUNOLOGY OF DIABETES II: PATHOGENESIS FROM MOUSE TO MAN | 2003年 / 1005卷

关键词：

diabetes; NOD; transcriptome; autoimmune; T cell;

D O I：

10.1196/annals.1288.017

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Transcriptome analysis is a powerful tool to characterize changes in leukocyte gene expression patterns and reveal very early molecular abnormalities in tissue. Herein, we report on characterization of the very earliest abnormalities in the transcriptome of leukocytes from young "prepathologic" NOD and NON female mice.

引用

页码：157 / 160

页数：4